[zuxul]

И так, получилось:

var data:BitmapDate = ...
invert_date = new BitmapData(date.width, date.height, true, 0x00000000);
var r:Rectangle = new Rectangle(0, 0, date.width, date.height);
var byte:ByteArray = date.getPixels(r);
var new_byte:ByteArray = new ByteArray();
byte.position = 0;
var length:int = byte.length >> 2; // == byte.length / 4
for (var i:int = 0; i < length; i++) {
    new_byte.writeInt(byte.readInt() ^ 0xFF000000);
}
new_byte.position = 0;
invert_date.setPixels(r, new_byte);